Plastic roads: not all they’re paved up to be

All roads do not lead to Rome.

REGIONAL anesthesia has evolved in recent years from a technique into an art, practiced by some pioneering anesthesiologists. As with any art form, regional anesthesia has obtained a level of complexity not seen before. Until recently, regional anesthesia was used by a select group, using sophisticated wording and techniques that prohibited its widespread implementation. However, with the devel...

Sex: Not all that it’s cracked up to be?

While sexual reproduction is generally thought to be, evolutionarily speaking, a good idea, there are a small number of organisms that are testament to the contrary. The root-knot nematodes Meloidogyne incognita, M. javanica, and M. arenaria reproduce clonally using mitotic parthenogenesis but have a broader host range, a wider geographical distribution, and a greater agricultural impact than t...

All Roads Lead To Rome

Legendary mathematician Paul Erdos liked to talk about the perfect proofs of mathematical theorems maintained by God. In [1], six different proofs are given to the infinity of prime numbers. Unlike mathematical proofs which are mentally reproducible objects, signal processing researchers can have an intimate discussion with God by creating computational algorithms which are experimentally repro...

All Roads Lead to IKKɛ

During malignant transformation, cancer cells acquire genetic alterations that surmount the normal controls regulating proliferation and cell survival. High-resolution comparative genomic analyses reveal that genomic instability is a hallmark of cancer development and that cancer-causing mutations are only a tiny fraction of the genetic modifications, most of which are “bystander” mutations. Th...

All roads lead to the insula.